Search results for "Norovirus GII"

showing 4 items of 4 documents

Free Chlorine and Peroxynitrite Alter the Capsid Structure of Human Norovirus GII.4 and Its Capacity to Bind Histo-Blood Group Antigens

2021

Human noroviruses (HuNoVs) are one of the leading causes of acute gastroenteritis worldwide. HuNoVs are frequently detected in water and foodstuffs. Free chlorine and peroxynitrite (ONOO−) are two oxidants commonly encountered by HuNoVs in humans or in the environment during their natural life cycle. In this study, we defined the effects of these two oxidants on GII.4 HuNoVs and GII.4 virus-like particles (VLPs). The impact on the capsid structure, the major capsid protein VP1 and the ability of the viral capsid to bind to histo-blood group antigens (HBGAs) following oxidative treatments were analyzed. HBGAs are attachment factors that promote HuNoV infection in human hosts. Overall, our re…

Microbiology (medical)viral proteinViral protein[SDV]Life Sciences [q-bio]viruseslcsh:QR1-502noroviruschemistry.chemical_elementvirus-like particlesmedicine.disease_causeMicrobiologylcsh:MicrobiologyperoxynitriteMicrobiologyBlood group antigens03 medical and health scienceschemistry.chemical_compoundAntigenmedicineChlorineOriginal Research030304 developmental biologyNorovirus GII0303 health sciences030306 microbiologyChemistryvirus diseasesfree chlorinebiochemical phenomena metabolism and nutrition3. Good healthCapsid[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyNorovirushisto-blood group antigensPeroxynitriteFrontiers in Microbiology
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Nearly Complete Genome Sequence of a Human Norovirus GII.P17-GII.17 Strain Isolated from Brazil in 2015

2019

Human noroviruses are the most common cause of nonbacterial acute gastroenteritis worldwide. We report here the nearly complete genome sequence (7,551 nucleotides) of a human norovirus GII.P17-GII.17 strain detected in July 2015 in the stool sample from an adult with acute gastroenteritis in Brazil.

0301 basic medicineWhole genome sequencingNorovirus GIIStool sampleVirus RNAStrain (biology)virusesGenome SequencesMicrobiologiavirus diseasesBiologyAcute gastroenteritismedicine.disease_causeGenoma humàVirology03 medical and health sciences030104 developmental biology0302 clinical medicinefluids and secretionsImmunology and Microbiology (miscellaneous)GeneticsNorovirusmedicine030212 general & internal medicineMolecular BiologyMicrobiology Resource Announcements
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Norovirus GII.17 as Major Epidemic Strain in Italy, Winter 2015–16

2017

In winter 2015-16, norovirus GII.17 Kawasaki 2014 emerged as a cause of sporadic gastroenteritis in children in Italy. Median patient age was higher for those with GII.17 than GII.4 infection (55 vs. 24 months), suggesting limited cross-protection for older children.

0301 basic medicineSettore MED/07 - Microbiologia E Microbiologia ClinicaEpidemiologyviruseslcsh:Medicinemedicine.disease_causeDisease Outbreaksfluids and secretionsEpidemiologyChildEpidemic strainCaliciviridae InfectionsNorovirus GIIvirus diseasesInfectious DiseasesItalyChild PreschoolPopulation SurveillanceSeasonsgastroenteritigastroenteritisNorovirus GII.17 as Major Epidemic Strain in Italy Winter 2015–16Microbiology (medical)medicine.medical_specialtyAdolescentGenotype030106 microbiologyenteric infectionHistory 21st Centurylcsh:Infectious and parasitic diseasesOpen Reading Frames03 medical and health sciencesPatient ageResearch LettermedicineHumansviruseslcsh:RC109-216Noroviruvirusebusiness.industryenteric infectionsNoroviruslcsh:RInfant NewbornInfantGII.17 Kawasaki 2014Virology030104 developmental biologyNorovirusbusinessEmerging Infectious Diseases
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Recombinant norovirus GII.g/GII.12 gastroenteritis in children.

2011

Recombinant GII.g/GII.12 norovirus (NoV) strains emerged in 2008 in Australia and subsequently have been associated with gastroenteritis outbreaks worldwide. In the winter season 2009-2010 GII.12 strains caused 16% of the NoV outbreaks in the United States. During 2009-2010 we also identified GII.g/GII.12 strains during surveillance of sporadic cases of gastroenteritis in Italian children. Severity scores were calculated for the GII.g/GII.12 NoV infections using the Vesikari scale and in two out of three paediatric cases they exceeded the median value calculated for concomitant GII.4 infections. Upon sequence analysis, the Italian strains were found to be recombinant viruses and displayed d…

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia Clinicacongenital hereditary and neonatal diseases and abnormalitiesGenotypeSequence analysisvirusesBiologyNorovirus GII.g GII.12 Gastroenteritis Italy Recombinationmedicine.disease_causeMicrobiologylaw.inventionMicrobiologyDisease Outbreaksfluids and secretionsViral geneticslawGenotypeGeneticsmedicineHumansChildMolecular BiologyEcology Evolution Behavior and SystematicsPhylogenyNorovirus GIIRecombination GeneticPolymorphism GeneticNorovirusvirus diseasesOutbreakInfantSequence Analysis DNAVirologyGastroenteritisPhylogeographyInfectious DiseasesItalyChild PreschoolNorovirusRecombinant DNARNA ViralCapsid ProteinsWinter seasonInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
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